Hypersensitivity reactions to beta-lactams in children
نویسندگان
چکیده
منابع مشابه
Diagnosing hypersensitivity reactions to cephalosporins in children.
OBJECTIVES The goals were to evaluate the usefulness of skin tests, patch tests, serum specific IgE assays, and challenges in diagnosing hypersensitivity reactions to cephalosporins and to clarify the pathogenic mechanism of such reactions. METHODS Children with immediate manifestations (within 1 hour) underwent immediate-reading skin tests with penicillin reagents and any suspect cephalospor...
متن کاملIs an extensive allergy diagnosis workup needed in all cases of suspected hypersensitivity to beta-lactams in children?
Results Eighty children (56.2% females) with a mean age of 6.7 yrs (SD=4.035) where evaluated for 83 suspected BL HSR. The mean time elapsed between the reaction and the clinical assessment was of 3.1 yrs (SD=3.36). The most frequently implicated drugs were amoxicillin/ clavulanate (54.2%) and amoxicillin (32.5%). BL were prescribed for tonsillitis in 32.5%, otitis in 21.7% and upper airways in...
متن کاملEvaluation of type I drug hypersensitivity reactions caused by chemotherapy in hospitalized children
Background and Objective: Type I drug hypersensitivity reactions causes immune responses that could endanger life. Therefore this study was designed with the aim of evaluation and register reactions that caused by chemotherapy in hospitalized children in Rasoul Akram Hospital in 2015. Methods: This is a descriptive, cross sectional study. All statistical calculation was performed using the v...
متن کاملHypersensitivity reactions to metronidazole.
BACKGROUND Hypersensitivity reactions to metronidazole are infrequently described. However, we believe that such reactions are increasing due to growing use of the drug for the treatment of amebiasis and anaerobe infections combined with other antibiotics. The present study assesses the need for oral provocation in patients with probable hypersensitivity reactions to metronidazole. METHODS We...
متن کاملHypersensitivity Reactions to Nonsteroidal Anti-inflammatory Drugs in Children and Adolescents: Selective Reactions.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are used throughout the world to treat pain and inflammation; however, they can trigger several types of drug hypersensitivity reactions (DHRs) in all age groups. Although most such reactions occur through activation of the leukotriene pathway without specific immunological recognition (cross-intolerance), a significant number of DHRs to NSAIDs are ...
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ژورنال
عنوان ژورنال: Current Opinion in Allergy & Clinical Immunology
سال: 2018
ISSN: 1528-4050,1473-6322
DOI: 10.1097/aci.0000000000000453